Which salutation is most appropriate for business correspondence?

The most appropriate salutation for business correspondence is "Dear Mr. Goodwin." This format adheres to standard business etiquette, using a respectful title and the individual's last name. By addressing the recipient with "Mr." followed by their surname, it maintains a professional tone and shows proper respect, which is essential in business communications.

In contrast, other options may lack formality or specificity. For instance, using a first name, as in "Dear Dennis," is generally too informal for professional correspondence unless there is an established rapport. The greeting "Dear Mr. Mark Smith M.D." might be perceived as overly formal or cumbersome since including both the title and the degree can be redundant after the name has been introduced. "Re: Jane Hudley" is not a suitable salutation at all; it suggests a subject line rather than addressing a person directly. Overall, "Dear Mr. Goodwin" is the most effective and appropriate choice in a business context.